Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | DHODH | Q02127 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8326298 | 0.85 | KDM4E (0.60) | KDM4EALDH1A1HSD17B10DHODHLMNA | |
| SCHEMBL8322325 | 0.82 | MEN1 (0.44) | KDM4EALDH1A1HSD17B10DHODHMAPT | |
| SCHEMBL6183169 | 0.77 | DHODH (0.85) | KDM4EALDH1A1HSD17B10DHODHLMNA | |
| SCHEMBL8329204 | 0.76 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10DHODHLMNA | |
| SCHEMBL1898810 | 0.75 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10DHODHLMNA | |
| SCHEMBL2783593 | 0.73 | KDM4E (0.79) | KDM4EALDH1A1HSD17B10DHODHLMNA | |
| SCHEMBL8327199 | 0.73 | KDM4E (0.74) | KDM4EALDH1A1HSD17B10DHODHLMNA | |
| SCHEMBL8321335 | 0.73 | ALDH1A1 (0.79) | KDM4EALDH1A1HSD17B10DHODHLMNA | |
| SCHEMBL15566039 | 0.73 | ALDH1A1 (0.67) | KDM4EALDH1A1HSD17B10DHODHLMNA | |
| SCHEMBL30049727 | 0.73 | ALDH1A1 (0.67) | KDM4EALDH1A1HSD17B10DHODHLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709377-B1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS CO LTD (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-5780634-A | Process for producing 2-(carboxyphenyl)-4-quinolinecarboxylic acid compounds | THE GREEN CROSS CORPORATION (JP) | 1998-07-14 | — | — | US | disclosed |
| EP-0709377-A1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS COMPANY LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |