Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321360 | 0.96 | KDM4E (0.69) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8687997 | 0.90 | KDM4E (0.64) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL1898810 | 0.85 | KDM4E (1.00) | KDM4EALDH1A1HSD17B10DHODHMAPK1 | |
| SCHEMBL8717010 | 0.84 | KDM4E (0.54) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8326754 | 0.84 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8324531 | 0.83 | MEN1 (0.77) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8322442 | 0.83 | KDM4E (0.55) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8618627 | 0.82 | ALDH1A1 (0.65) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8321362 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8329204 | 0.81 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0709377-B1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS CO LTD (JP) | 1999-09-29 | — | — | EP | claimed |
| EP-0693478-B1 | Quinoline compounds | GREEN CROSS CORP (JP) | 1998-08-12 | — | — | EP | claimed |
| US-5780634-A | Process for producing 2-(carboxyphenyl)-4-quinolinecarboxylic acid compounds | THE GREEN CROSS CORPORATION (JP) | 1998-07-14 | — | — | US | claimed |
| US-5665881-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE, ANGIOTENSIN II ANTAGONIST | THE GREEN CROSS CORPORATION (JP) | 1997-09-09 | — | — | US | claimed |
| EP-0709377-A1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS COMPANY LTD. (JP) | 1996-05-01 | — | — | EP | claimed |
| EP-0693478-A1 | Quinoline compounds | THE GREEN CROSS CORPORATION (JP) | 1996-01-24 | — | — | EP | claimed |
| JP-8119941-A | — | — | None | — | — | JP | disclosed |
| JP-6016641-A | — | — | None | — | — | JP | disclosed |
| EP-0709377-B1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS CO LTD (JP) | 1999-09-29 | — | — | EP | disclosed |
| EP-0693478-B1 | Quinoline compounds | GREEN CROSS CORP (JP) | 1998-08-12 | — | — | EP | disclosed |
| US-5780634-A | Process for producing 2-(carboxyphenyl)-4-quinolinecarboxylic acid compounds | THE GREEN CROSS CORPORATION (JP) | 1998-07-14 | — | — | US | disclosed |
| US-5665881-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE, ANGIOTENSIN II ANTAGONIST | THE GREEN CROSS CORPORATION (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0569013-B1 | Quinoline compounds as angiotensin II antagonists | GREEN CROSS CORP (JP) | 1996-08-28 | — | — | EP | disclosed |
| JP-H08119941-A | PRODUCTION OF QUINOLINE-2-YLBENZOIC ACIDS | ASAHI GLASS CO LTD | 1996-05-14 | — | — | JP | disclosed |
| EP-0709377-A1 | Process for producing quinolin-2-yl benzoic acid compounds | ASAHI GLASS COMPANY LTD. (JP) | 1996-05-01 | — | — | EP | disclosed |
| EP-0693478-A1 | Quinoline compounds | THE GREEN CROSS CORPORATION (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5478832-A | Angiotensin II antagonists; cardiovascular disorders | THE GREEN CROSS CORPORATION (JP) | 1995-12-26 | — | — | US | disclosed |
| JP-H0616641-A | QUINOLIN-2-YLBENZOIC ACID DERIVATIVE AND ITS PRODUCTION | ASAHI GLASS CO LTD | 1994-01-25 | — | — | JP | disclosed |
| EP-0569013-A1 | Quinoline compounds as angiotensin II antagonists | THE GREEN CROSS CORPORATION (JP) | 1993-11-10 | — | — | EP | disclosed |