Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL839809 | 0.94 | KIF11 (0.59) | KIF11LMNABACE1HSD17B10HPGD | |
| SCHEMBL4829620 | 0.89 | KIF11 (0.69) | KIF11LMNABACE1HSD17B10HPGD | |
| SCHEMBL21991243 | 0.87 | KIF11 (0.56) | KIF11BACE1HSD17B10HPGDKDM4E | |
| SCHEMBL3420307 | 0.86 | KIF11 (0.51) | KIF11LMNABACE1HPGDALDH1A1 | |
| SCHEMBL23059793 | 0.84 | KIF11 (0.50) | KIF11LMNABACE1HSD17B10HPGD | |
| SCHEMBL11059672 | 0.84 | PRSS1 (0.62) | KIF11LMNAHSD17B10CYP2C19ELANE | |
| SCHEMBL5027571 | 0.84 | LMNA (0.70) | LMNAHSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL9760958 | 0.84 | LMNA (0.70) | LMNAHSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL21991789 | 0.82 | KIF11 (0.51) | KIF11LMNAKDM4EALDH1A1ELANE | |
| SCHEMBL3368661 | 0.81 | MAPT (0.70) | LMNABACE1HPGDKDM4ECYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556381-B1 | N-(4-PYRIDYL OR 4-QUINOLINYL) ARYLACETAMIDE PESTICIDES | DOW AGROSCIENCES LLC (US) | 1999-04-28 | — | — | EP | disclosed |
| EP-0555469-A4 | 4-(ARALKOXY OR ARALKYLAMINO)PYRIDINE PESTICIDES----------------- | DOWELANCO (US) | 1995-06-21 | — | — | EP | disclosed |
| EP-0556381-A4 | — | DOWELANCO (US) | 1995-06-21 | — | — | EP | disclosed |
| US-5399564-A | N-(4-pyridyl or 4-quinolinyl) arylacetamide and 4-(aralkoxy or aralkylamino) pyridine pesticides | DOWELANCO (US) | 1995-03-21 | — | — | US | disclosed |
| EP-0556381-A1 | N-(4-PYRIDYL OR 4-QUINOLINYL) ARYLACETAMIDE PESTICIDES | DOWELANCO (US) | 1993-08-25 | — | — | EP | disclosed |
| EP-0555469-A1 | 4-(ARALKOXY OR ARALKYLAMINO)PYRIDINE PESTICIDES----------------- | DOWELANCO (US) | 1993-08-18 | — | — | EP | disclosed |
| WO-1993004580-A1 | N-(4-PYRIDYL OR 4-QUINOLINYL) ARYLACETAMIDE PESTICIDES | DOWELANCO (US) | 1993-03-18 | — | — | WO | disclosed |
| WO-1993005050-A1 | 4-(ARALKOXY OR ARALKYLAMINO)PYRIDINE PESTICIDES_________________ | DOWELANCO (US) | 1993-03-18 | — | — | WO | disclosed |