SCHEMBL839809

SCHEMBL839809

CC(=O)Oc1ccc(C(F)(F)F)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.59
LMNA P02545 1/20 0.57
ALDH1A1 P00352 3/20 0.53
HSD17B10 Q99714 2/20 0.53
KDM4E B2RXH2 1/20 0.53
USP2 O75604 1/20 0.53
HPGD P15428 1/20 0.53
CYP2C19 P33261 1/20 0.53
BACE1 P56817 1/20 0.53
MAPT P10636 2/20 0.52
POLB P06746 1/20 0.52
PKM P14618 1/20 0.52
CYP1A1 P04798 1/20 0.51
CYP1B1 Q16678 1/20 0.51
ELANE P08246 1/20 0.50
MAOB P27338 1/20 0.50
CES2 O00748 1/20 0.48
CES1 P23141 1/20 0.48
CYP11B1 P15538 1/20 0.48
CYP11B2 P19099 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8329346 0.94 KIF11 (0.54) KIF11LMNAALDH1A1HSD17B10KDM4E
SCHEMBL4829620 0.94 KIF11 (0.69) KIF11LMNAALDH1A1HSD17B10KDM4E
SCHEMBL11059672 0.89 PRSS1 (0.62) KIF11LMNAHSD17B10CYP2C19MAPT
SCHEMBL23059793 0.89 KIF11 (0.50) KIF11LMNAALDH1A1HSD17B10KDM4E
SCHEMBL15453601 0.85 KIF11 (0.61) KIF11ALDH1A1HSD17B10KDM4EUSP2
SCHEMBL6939142 0.84 LMNA (0.53) KIF11LMNAALDH1A1HSD17B10KDM4E
SCHEMBL3420665 0.84 KIF11 (0.56) KIF11ALDH1A1HSD17B10KDM4EUSP2
SCHEMBL28911333 0.84 CYP1A1 (0.57) LMNAKDM4EMAPTCYP1A1CYP1B1
SCHEMBL9257680 0.83 KIF11 (0.53) KIF11ALDH1A1BACE1MAOBCES2
SCHEMBL1720744 0.83 KIF11 (0.63) KIF11ALDH1A1MAOBCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116082720-A High-strength super-wear-resistant rubber conveyer belt and production method thereof 河北九洲橡胶科技股份有限公司 2023-05-09 CN claimed
US-8952083-B2 Fluorocopolymer composition and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2015-02-10 US claimed
EP-4743178-A1 NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER AND METABOLIC DISEASES Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2026-05-20 EP disclosed
EP-4743447-A1 NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER AND METABOLIC DISEASES Katholieke Universiteit Leuven KU Leuven Research & Development (BE) 2026-05-20 EP disclosed
US-12392042-B2 Alternating current (AC) transition-metal catalysis YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2025-08-19 US disclosed
WO-2025111582-A1 AZA-TETRACYCLIC OXAZEPINE INHIBITORS OF KRAS-G12D GENENTECH, INC. (US) 2025-05-30 WO disclosed
CN-119430210-A Preparation method of hydrophobic synthetic mica 河南晶多多新材料科技有限公司 2025-02-14 CN disclosed
WO-2025016906-A1 NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER AND METABOLIC DISEASES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-01-23 WO disclosed
WO-2025016909-A1 NOVEL COMPOUNDS FOR THE TREATMENT OF CANCER AND METABOLIC DISEASES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2025-01-23 WO disclosed
EP-4482826-A1 DIHYDROQUINAZOLINONES AND RELATED ANALOGS FOR INHIBITING YAP/TAZ-TEAD The Katholieke Universiteit Leuven (BE) 2025-01-01 EP disclosed
CN-119191962-A Preparation method of a-deuterated carboxylic acid derivative compound 常州大学 2024-12-27 CN disclosed
US-4988810-A Chemical intermediates for central nervous system analgesics and antiarrhythmia agents ROUSSEL UCLAF (FR) 1991-01-29 US disclosed
US-4968700-A DIURETIC, HYPOTENSIVE, ANTIISCHEMIC, ANTIARRHYTHMIA ROUSSEL UCLAF (FR) 1990-11-06 US disclosed
EP-0298803-A1 Process for the perhaloalkylation of aromatic derivatives RHONE-POULENC CHIMIE (FR) 1989-01-11 EP disclosed
US-4761501-A INTERMEDIATES FOR ANTIDEPRESSANTS AMERICAN HOME PRODUCTS CORPORATION (US) 1988-08-02 US disclosed
EP-0112669-B1 PHENETHYLAMINE DERIVATIVES AND INTERMEDIATES THEREFOR AMERICAN HOME PRODUCTS CORPORATION (US) 1987-07-29 EP disclosed
EP-0206951-A2 Process for the perfluoroalkylation of aromatic derivatives RHONE-POULENC CHIMIE (FR) 1986-12-30 EP disclosed
US-4611078-A ANTIDEPRESSANT INTERMEDIATES AMERICAN HOME PRODUCTS CORPORATION (US) 1986-09-09 US disclosed
US-4535186-A CENTRAL NERVOUS SYSTEM ANTIDEPRESSANTS; VENLAFAXINE AMERICAN HOME PRODUCTS CORPORATION (US) 1985-08-13 US disclosed
EP-0112669-A2 Phenethylamine derivatives and intermediates therefor AMERICAN HOME PRODUCTS CORPORATION (US) 1984-07-04 EP disclosed