SCHEMBL8329367

SCHEMBL8329367

CC(C)(C)OC(=O)N(CCN(CCOCc1ccccc1)CCOCc1ccccc1)C(=O)OC(C)(C)C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.58
PPARA Q07869 2/20 0.44
NPSR1 Q6W5P4 1/20 0.42
ALDH1A1 P00352 1/20 0.40
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40
PPARG P37231 1/20 0.40
AKT1 P31749 1/20 0.40
TSHR P16473 1/20 0.40
CHRM2 P08172 1/20 0.39
CHRM4 P08173 1/20 0.39
CHRM5 P08912 1/20 0.39
CHRM1 P11229 1/20 0.39
CHRM3 P20309 1/20 0.39
CTSB P07858 1/20 0.39
CTSS P25774 1/20 0.39
HDAC3 O15379 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC2 Q92769 1/20 0.39
NCOR2 Q9Y618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7754342 0.83 L3MBTL1 (0.57) L3MBTL1PPARANPSR1ALDH1A1LMNA
SCHEMBL16993182 0.82 L3MBTL1 (0.62) L3MBTL1PPARANPSR1ALDH1A1LMNA
SCHEMBL4344800 0.80 L3MBTL1 (0.59) L3MBTL1PPARANPSR1ALDH1A1LMNA
SCHEMBL8501723 0.80 L3MBTL1 (0.59) L3MBTL1PPARANPSR1ALDH1A1LMNA
SCHEMBL6987866 0.80 L3MBTL1 (0.59) L3MBTL1PPARANPSR1ALDH1A1LMNA
SCHEMBL25985039 0.80 L3MBTL1 (0.50) L3MBTL1PPARAALDH1A1LMNAHTT
SCHEMBL4344803 0.79 L3MBTL1 (0.58) L3MBTL1PPARANPSR1ALDH1A1LMNA
SCHEMBL3488737 0.78 L3MBTL1 (0.52) L3MBTL1PPARANPSR1ALDH1A1LMNA
SCHEMBL3488741 0.78 L3MBTL1 (0.52) L3MBTL1PPARANPSR1ALDH1A1LMNA
SCHEMBL16772764 0.78 L3MBTL1 (0.57) L3MBTL1PPARANPSR1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5972307-A ADMINISTERING TO HUMAN OR ANIMAL BODY AN EFFECTIVE AMOUNT OF A DIAGNOSTIC AGENT COMPRISES A METAL CHELATE OF A COMPOUND HAVING TWO MACROCYCLIC CHELANT GROUPS LINKED BY A BRIDGE CONTAINING ESTER OR AMIDE BOND NYCOMED SALUTAR, INC. (US) 1999-10-26 US disclosed