Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | STAT3 | P40763 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3346514 | 0.91 | CA12 (0.41) | CA12CA1CA9PSMD10ALDH1A1 | |
| SCHEMBL18263804 | 0.85 | CA12 (0.37) | CA12CA1CA9PSMD10ALDH1A1 | |
| SCHEMBL11484074 | 0.85 | ALDH1A1 (0.41) | CA12CA1CA9PSMD10ALDH1A1 | |
| SCHEMBL17006286 | 0.82 | VDR (0.40) | CA12CA1CA9ALDH1A1CYP3A4 | |
| SCHEMBL20438608 | 0.82 | CA12 (0.42) | CA12CA1CA9PSMD10ALDH1A1 | |
| SCHEMBL18263758 | 0.79 | CA1 (0.39) | CA12CA1CA9PSMD10ALDH1A1 | |
| SCHEMBL483847 | 0.79 | ALDH1A1 (0.50) | CA12CA1CA9PSMD10ALDH1A1 | |
| SCHEMBL890725 | 0.79 | ALDH1A1 (0.50) | CA12CA1CA9PSMD10ALDH1A1 | |
| SCHEMBL278880 | 0.79 | ALDH1A1 (0.41) | CA12CA1CA9PSMD10ALDH1A1 | |
| SCHEMBL9501782 | 0.79 | L3MBTL1 (0.47) | CA12CA1CA9PSMD10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947515-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-10-06 | — | — | EP | disclosed |
| US-5843957-A | Naphthyridine derivatives | SUMITOMO PHARMACEUTICALS COMPANY, LTD. (JP) | 1998-12-01 | — | — | US | disclosed |