Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 7/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PTAFR | P25105 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329403 | 1.00 | CHRNA7 (0.54) | CHRNA7TBXAS1CYP2A6TDP1L3MBTL1 | |
| SCHEMBL10987324 | 0.90 | CHRNA7 (0.56) | CHRNA7TBXAS1CYP2A6TDP1L3MBTL1 | |
| SCHEMBL29883579 | 0.84 | CYP19A1 (0.47) | TBXAS1TDP1LMNA | |
| SCHEMBL10515846 | 0.84 | LMNA (0.64) | TDP1LMNA | |
| SCHEMBL2954088 | 0.82 | CHRNA7 (0.63) | CHRNA7TBXAS1CYP2A6TDP1L3MBTL1 | |
| SCHEMBL16244732 | 0.82 | LMNA (0.66) | CHRNA7TBXAS1CYP2A6TDP1L3MBTL1 | |
| SCHEMBL8152377 | 0.81 | CHRNA7 (0.59) | CHRNA7TBXAS1CYP2A6TDP1L3MBTL1 | |
| SCHEMBL10426928 | 0.81 | CHRNB2 (0.48) | CHRNA7TBXAS1TDP1L3MBTL1LMNA | |
| SCHEMBL10426927 | 0.81 | CHRNB2 (0.48) | CHRNA7TBXAS1TDP1L3MBTL1LMNA | |
| SCHEMBL8746602 | 0.79 | CHRNA7 (0.59) | CHRNA7TBXAS1CYP2A6TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0943615-A1 | 1,4-DIHYDROPYRIDINE DERIVATIVES | Nikken Chemicals Company, Limited (JP) | 1999-09-22 | — | — | EP | disclosed |