SCHEMBL832944

SCHEMBL832944

C=Cc1ccc(NC(=O)CC(C)=O)cc1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.57
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
CA4 P22748 1/20 0.54
CA7 P43166 1/20 0.54
POLB P06746 4/20 0.53
TSHR P16473 1/20 0.53
KDM4E B2RXH2 3/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ALDH1A1 P00352 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP2C19 P33261 1/20 0.50
HIF1A Q16665 1/20 0.50
THRB P10828 1/20 0.44
TP53 P04637 1/20 0.41
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL593172 0.84 MAPT (0.74) MAPTCA1CA2CA4CA7
SCHEMBL13112978 0.84 POLB (0.46) MAPTPOLBKDM4EMEN1KMT2A
SCHEMBL21177278 0.84 MAPT (0.59) MAPTCA1CA2CA4CA7
SCHEMBL13101226 0.82 KMT2A (0.44) MAPTPOLBKDM4EMEN1KMT2A
SCHEMBL2056453 0.81 SMN1; SMN2 (0.59) MAPTCA1CA2CA4CA7
SCHEMBL9113346 0.80 MAOB (0.45) MAPTPOLBKDM4EMEN1KMT2A
SCHEMBL8428153 0.80 NPC1 (0.58) MAPTPOLBKDM4EMEN1KMT2A
SCHEMBL29331005 0.79 MEN1 (0.45) MAPTPOLBTSHRKDM4EMEN1
SCHEMBL6204592 0.79 MAPT (0.67) MAPTCA1CA2CA4CA7
Hydrochloric Acid SCHEMBL9756650 0.78 SCN1A (0.50) MAPTCA1CA2POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8142842-B2 porous ink-receptive layer contains inorganic fine particles having average secondary particle size of 500 nm or less and resin binder on the support; front surface layer containing an acrylic resin emulsion on ink-receptive layer; excellent coloring property, ink drying property, and scratch resistance MITSUBISHI PAPER MILLS LIMITED (JP) 2012-03-27 US disclosed
US-8087767-B2 Inkjet ink set E. I. DU PONT DE NEMOURS AND COMPANY (US) 2012-01-03 US disclosed
EP-1916118-B1 Ink-jet recording material MITSUBISHI PAPER MILLS LTD (JP) 2009-07-29 EP disclosed
EP-1916118-A1 Ink-jet recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2008-04-30 EP disclosed
US-20080095948-A1 Ink-jet recording method MITSUBISHI PAPER MILLS LIMITED 2008-04-24 US disclosed
US-20070211126-A1 Inkjet ink set E. I. DU PONT DE NEMOURS AND COMPANY 2007-09-13 US disclosed