Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL832944 | 0.78 | MAPT (0.57) | CYP1A2CYP2C19MEN1KMT2AALDH1A1 | |
| SCHEMBL9113346 | 0.76 | MAOB (0.45) | MEN1KMT2AALDH1A1KDM4ETHRB | |
| SCHEMBL13112978 | 0.76 | POLB (0.46) | MEN1KMT2AALDH1A1KDM4ETHRB | |
| SCHEMBL8428153 | 0.76 | NPC1 (0.58) | MEN1KMT2AALDH1A1LMNAKDM4E | |
| SCHEMBL13901427 | 0.75 | SCN1A (0.76) | SCN1ASCN2ASCN3ACYP1A2CYP2C19 | |
| SCHEMBL13101226 | 0.75 | KMT2A (0.44) | MEN1KMT2AALDH1A1KDM4ETHRB | |
| SCHEMBL8426259 | 0.73 | THRB (0.50) | ALDH1A1KDM4ETHRBPOLBMAPT | |
| SCHEMBL2056453 | 0.73 | SMN1; SMN2 (0.59) | CYP2C19MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL14301433 | 0.73 | RAB9A (0.52) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL7653547 | 0.73 | SCN1A (0.51) | SCN1ASCN2ASCN3ACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249991-B1 | COLOR FILTER ARRAYS | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1991-08-28 | — | — | EP | disclosed |
| EP-0358439-A1 | Improved magenta filters for filter arrays | EASTMAN KODAK COMPANY (US) | 1990-03-14 | — | — | EP | disclosed |
| EP-0249991-A2 | Color filter arrays | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1987-12-23 | — | — | EP | disclosed |
| US-4247615-A | DIAZO RESIN, MORDANT FOR ANIONIC DYE | EASTMAN KODAK COMPANY (US) | 1981-01-27 | — | — | US | disclosed |
| US-4220700-A | MORDANTS, ANIONIC DYES | EASTMAN KODAK COMPANY (US) | 1980-09-02 | — | — | US | disclosed |