Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.49 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.49 |
| ▸ | THRA | P10827 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.45 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8333855 | 1.00 | CYSLTR2 (0.49) | CYSLTR2CYSLTR1THRATHRBKDM4E | |
| SCHEMBL8721505 | 0.89 | KDM4E (0.46) | CYSLTR2CYSLTR1KDM4EALDH1A1LMNA | |
| SCHEMBL8330948 | 0.89 | MTNR1A (0.45) | CYSLTR2CYSLTR1KDM4EALDH1A1LMNA | |
| SCHEMBL8331610 | 0.89 | MTNR1A (0.45) | CYSLTR2CYSLTR1KDM4EALDH1A1LMNA | |
| SCHEMBL8329274 | 0.89 | MTNR1A (0.45) | CYSLTR2CYSLTR1KDM4EALDH1A1LMNA | |
| SCHEMBL8333540 | 0.88 | MTNR1A (0.46) | CYSLTR2CYSLTR1KDM4EALDH1A1LMNA | |
| SCHEMBL8333977 | 0.86 | ALDH1A1 (0.40) | KDM4EALDH1A1LMNASMN1; SMN2CACNA1B | |
| SCHEMBL8332766 | 0.85 | BCHE (0.41) | KDM4EALDH1A1LMNASMN1; SMN2CACNA1B | |
| SCHEMBL8332918 | 0.85 | ALOX5 (0.44) | KDM4EALDH1A1LMNASMN1; SMN2ALOX5 | |
| SCHEMBL8331870 | 0.84 | KDM4E (0.38) | CYSLTR2CYSLTR1KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753709-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-19 | — | — | US | disclosed |