Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | ACR | P10323 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328700 | 0.95 | L3MBTL1 (0.56) | KMT2AL3MBTL1ALDH1A1LMNAMAPK1 | |
| SCHEMBL8328036 | 0.93 | L3MBTL1 (0.53) | KMT2AL3MBTL1ALDH1A1LMNAMAPK1 | |
| SCHEMBL8331355 | 0.92 | L3MBTL1 (0.52) | KMT2AL3MBTL1ALDH1A1LMNAMAPK1 | |
| SCHEMBL8332709 | 0.88 | MAPT (0.56) | KMT2ALMNACCNCCDK8PDGFRB | |
| SCHEMBL13806837 | 0.83 | L3MBTL1 (0.59) | KMT2AL3MBTL1ALDH1A1LMNANPC1 | |
| SCHEMBL20628415 | 0.82 | LMNA (0.60) | KMT2AL3MBTL1ALDH1A1LMNANPC1 | |
| SCHEMBL23556207 | 0.81 | L3MBTL1 (0.52) | KMT2AL3MBTL1ALDH1A1LMNACCNC | |
| SCHEMBL738854 | 0.79 | MAPT (0.56) | KMT2AL3MBTL1ALDH1A1LMNANPC1 | |
| SCHEMBL5850083 | 0.79 | MAPT (0.56) | KMT2AL3MBTL1ALDH1A1LMNANPC1 | |
| SCHEMBL15672803 | 0.79 | HGFAC (0.59) | KMT2AALDH1A1LMNACCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540609-B1 | CEPHALOSPORINS AND HOMOLOGUES, PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS | PFIZER (US) | 1999-10-13 | — | — | EP | disclosed |
| US-5900145-A | CROSSLINKED POLYSILOXANE LAYER HAVING AN AROMATIC LIQUID CRYSTAL SIDECHAIN INCLUDING A 2,6-NAPHTHALENE OR 4,4'-DIPHENYLENE GROUP; SEPARATION OF ISOMERS OF AROMATIC HYDROCARBONS, HALOGENATED AROMATIC TOXIC HYDROCARBONS | J & K ENVIRONMENTAL LTD. (CA) | 1999-05-04 | — | — | US | disclosed |