Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CCNC | P24863 | 1/20 | 0.45 |
| ▸ | CDK8 | P49336 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23386424 | 0.89 | MAPT (0.49) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL8328700 | 0.88 | L3MBTL1 (0.56) | NPC1SMN1; SMN2KMT2ALMNACCNC | |
| SCHEMBL8329494 | 0.88 | KMT2A (0.50) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL8328036 | 0.85 | L3MBTL1 (0.53) | NPC1SMN1; SMN2KMT2ALMNA | |
| SCHEMBL8331355 | 0.84 | L3MBTL1 (0.52) | MAPTNPC1POLBSMN1; SMN2KMT2A | |
| SCHEMBL10958710 | 0.83 | MAPT (0.48) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL26041373 | 0.82 | CA1 (0.49) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL7619158 | 0.82 | NPC1 (0.52) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL8026374 | 0.82 | NPC1 (0.52) | MAPTNPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL15672803 | 0.81 | HGFAC (0.59) | MAPTPOLBRAB9AKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5900145-A | CROSSLINKED POLYSILOXANE LAYER HAVING AN AROMATIC LIQUID CRYSTAL SIDECHAIN INCLUDING A 2,6-NAPHTHALENE OR 4,4'-DIPHENYLENE GROUP; SEPARATION OF ISOMERS OF AROMATIC HYDROCARBONS, HALOGENATED AROMATIC TOXIC HYDROCARBONS | J & K ENVIRONMENTAL LTD. (CA) | 1999-05-04 | — | — | US | disclosed |