Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | WRN | Q14191 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329530 | 0.80 | KMT2A (0.39) | MAPK1WRNALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6589030 | 0.79 | PRKCA (0.39) | MAPK1WRNALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL727818 | 0.74 | CYP3A4 (0.46) | MAPK1WRNALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL6591091 | 0.69 | KMT2A (0.38) | ALDH1A1SMN1; SMN2KDM4EHSD17B10L3MBTL1 | |
| SCHEMBL6595226 | 0.66 | CYP3A4 (0.63) | MAPK1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL10765175 | 0.66 | CA1 (0.56) | HPGDSMN1; SMN2MAPTTSHRCA12 | |
| SCHEMBL18823837 | 0.63 | CA1 (0.59) | ALDH1A1HPGDSMN1; SMN2MAPTTSHR | |
| SCHEMBL26325510 | 0.63 | CA12 (0.51) | MAPK1ALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL10382360 | 0.63 | HTT (0.42) | ALDH1A1SMN1; SMN2CA12CA1CA2 | |
| SCHEMBL570567 | 0.63 | LMNA (0.67) | ALDH1A1HPGDSMN1; SMN2MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |