Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MMP8 | P22894 | 2/20 | 0.50 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329553 | 0.93 | L3MBTL1 (0.51) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL13195088 | 0.92 | ALDH1A1 (0.51) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL20856858 | 0.89 | LMNA (0.48) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL9532125 | 0.86 | KMT2A (0.56) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL10937773 | 0.85 | ALDH1A1 (0.45) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL10472516 | 0.84 | L3MBTL1 (0.64) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL3813646 | 0.84 | L3MBTL1 (0.64) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL27358218 | 0.84 | L3MBTL1 (0.52) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL27583131 | 0.84 | L3MBTL1 (0.64) | L3MBTL1LMNAALDH1A1MMP8PIN1 | |
| SCHEMBL1232306 | 0.84 | ALDH1A1 (0.53) | L3MBTL1ALDH1A1KMT2AMEN1SLC1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |
| US-5637613-A | ANTITUMOR AGENT; IMMUNOSUPPRESSANTS | FOURNIER INDUSTRIE ET SANTE (FR) | 1997-06-10 | — | — | US | disclosed |
| US-5476870-A | Immunosuppressants | FOURNIER INDUSTRIE ET SANTE (FR) | 1995-12-19 | — | — | US | disclosed |
| US-4128425-A | PYRAZOLIDINONE DERIVATIVES | POLAROID CORPORATION (US) | 1978-12-05 | — | — | US | disclosed |