Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.41 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11139354 | 0.84 | CYP3A4 (0.42) | HSD17B10ALDH1A1HPGDSMN1; SMN2CYP3A4 | |
| SCHEMBL28781884 | 0.83 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTCYP3A4TSHR | |
| SCHEMBL4137976 | 0.81 | CYP2A6 (0.41) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL2563564 | 0.81 | EGFR (0.47) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL3976211 | 0.78 | CYP2A6 (0.52) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL11130220 | 0.78 | CYP2A6 (0.38) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL3985166 | 0.76 | ALDH5A1 (0.41) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL5429778 | 0.76 | CYP2A6 (0.50) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 | |
| SCHEMBL18427888 | 0.76 | HRH3 (0.41) | LMNACYP3A4TSHR | |
| SCHEMBL6599690 | 0.75 | CYP2A6 (0.39) | CYP2A6HSD17B10ALDH5A1ABATALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769445-A | Process for the solid phase synthesis of peptides which contain sulfated tyrosine | PENNWALT CORPORATION (US) | 1988-09-06 | — | — | US | claimed |
| EP-0161468-A2 | Process for the solid phase synthesis of peptides which contain sulfated tyrosine | PENNWALT CORPORATION (US) | 1985-11-21 | — | — | EP | claimed |
| US-4134768-A | Photographic uses of polyvinyl-phenylmercapto-tetrazoles | POLAROID CORPORATION (US) | 1979-01-16 | — | — | US | claimed |
| EP-0558671-B1 | SYNTHESIS OF EQUIMOLAR MULTIPLE OLIGOMER MIXTURES, ESPECIALLY OF OLIGOPEPTIDE MIXTURES | ITEREX PHARMA LP (US) | 1999-01-27 | — | — | EP | disclosed |
| US-5556762-A | Scanning synthetic peptide combinatorial libraries: oligopeptide mixture sets having a one predetermined residue at a single, predetermined position, methods of making and using the same | HOUGHTEN PHARMACEUTICAL INC. (US) | 1996-09-17 | — | — | US | disclosed |
| US-5504190-A | Equimolar multiple oligomer mixtures, especially oligopeptide mixtures | TORREY PINES INSTITUTE FOR MOLECULAR STUDIES (US) | 1996-04-02 | — | — | US | disclosed |
| EP-0558671-A4 | SYNTHESIS OF EQUIMOLAR MULTIPLE OLIGOMER MIXTURES, ESPECIALLY OF OLIGOPEPTIDE MIXTURES | ITEREX PHARMA LP (US) | 1994-05-11 | — | — | EP | disclosed |
| EP-0558671-A1 | SYNTHESIS OF EQUIMOLAR MULTIPLE OLIGOMER MIXTURES, ESPECIALLY OF OLIGOPEPTIDE MIXTURES | ITEREX PHARMACEUTICALS LTD. PARTNERSHIP (US) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992009300-A1 | SYNTHESIS OF EQUIMOLAR MULTIPLE OLIGOMER MIXTURES, ESPECIALLY OF OLIGOPEPTIDE MIXTURES | ITEREX PHARMACEUTICALS LTD. PARTNERSHIP (US) | 1992-06-11 | — | — | WO | disclosed |
| EP-0196174-B1 | MEANS FOR SEQUENTIAL SOLID PHASE ORGANIC SYNTHESIS AND METHODS USING THE SAME | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1990-01-17 | — | — | EP | disclosed |
| US-4769445-A | Process for the solid phase synthesis of peptides which contain sulfated tyrosine | PENNWALT CORPORATION (US) | 1988-09-06 | — | — | US | disclosed |
| US-4631211-A | REACTIVE PARTICLES ENCLOSED IN WATER AND SOLVENT-INSOLUBLE MESH CONTAINER; PEPTIDE SYNTHESIS | SCRIPPS CLINIC & RESEARCH FOUNDATION (US) | 1986-12-23 | — | — | US | disclosed |
| EP-0196174-A2 | Means for sequential solid phase organic synthesis and methods using the same | SCRIPPS CLINIC AND RESEARCH FOUNDATION (US) | 1986-10-01 | — | — | EP | disclosed |
| EP-0161468-A2 | Process for the solid phase synthesis of peptides which contain sulfated tyrosine | PENNWALT CORPORATION (US) | 1985-11-21 | — | — | EP | disclosed |