Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28006231 | 0.82 | AKR1C3 (0.43) | SRD5A2TSHRALOX15VCAM1KDM4E | |
| SCHEMBL10662231 | 0.80 | SRD5A2 (0.51) | SRD5A2TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10658402 | 0.75 | CYP3A4 (0.49) | SRD5A2TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6322177 | 0.74 | SRD5A2 (0.79) | SRD5A2TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11543650 | 0.73 | SRD5A2 (0.47) | SRD5A2TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10631217 | 0.71 | SRD5A2 (0.49) | SRD5A2TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11543646 | 0.71 | CYP2C9 (0.56) | SRD5A2TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL10727775 | 0.70 | SLC6A2 (0.60) | SRD5A2TSHRSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL4377122 | 0.70 | ALDH1A1 (0.50) | NPC1RAB9AKDM4EMEN1MAPT | |
| SCHEMBL11704979 | 0.68 | NR4A1 (0.52) | SRD5A2TSHRALOX15RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947516-A1 | N-benzyl substituted, heterocyclic ring-fused pyrimidinone derivatives, their preparation and their use as herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-10-06 | — | — | EP | disclosed |