SCHEMBL28006231

SCHEMBL28006231

O=[C]c1c(Cl)ccc(C(=O)c2ccccc2)c1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.43
ALDH1A1 P00352 3/20 0.42
VCAM1 P19320 1/20 0.42
GAA P10253 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
NR4A1 P22736 1/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
KEAP1 Q14145 1/20 0.41
NFE2L2 Q16236 1/20 0.41
MAPT P10636 2/20 0.41
ALOX15 P16050 1/20 0.40
MAPK13 O15264 1/20 0.40
MAPK12 P53778 1/20 0.40
MAPK11 Q15759 1/20 0.40
MAPK14 Q16539 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.39
LMNA P02545 2/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2987573 0.84 ALDH1A1 (0.50) AKR1C3ALDH1A1VCAM1GAAMEN1
SCHEMBL5073237 0.84 ALDH1A1 (0.59) AKR1C3ALDH1A1GAAMEN1KMT2A
SCHEMBL8329659 0.82 SRD5A2 (0.49) ALDH1A1VCAM1MEN1KMT2AKDM4E
SCHEMBL31380407 0.77 MEN1 (0.49) AKR1C3ALDH1A1GAAMEN1KMT2A
SCHEMBL11882116 0.76 AKR1C3 (0.55) AKR1C3ALDH1A1GAAMEN1KMT2A
SCHEMBL27550919 0.75 AKR1C3 (0.48) AKR1C3ALDH1A1VCAM1GAAMEN1
SCHEMBL10455760 0.75 LMNA (0.58) AKR1C3ALDH1A1GAAMEN1KMT2A
SCHEMBL1812262 0.75 AKR1C3 (0.48) AKR1C3ALDH1A1GAAMEN1KMT2A
SCHEMBL6532690 0.74 NR4A1 (0.49) AKR1C3ALDH1A1GAAMEN1KMT2A
SCHEMBL10455799 0.74 KDM4E (0.49) AKR1C3ALDH1A1GAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104487462-A Photopolymerization method and novel compound used for the same LAMBSON LTD 2015-04-01 CN disclosed