Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | EED | O75530 | 1/20 | 0.40 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.40 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.40 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.40 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329687 | 0.94 | GPR119 (0.45) | HPGDGPR119RECQLEPHX1EED | |
| SCHEMBL19995830 | 0.81 | HPGD (0.48) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL30659463 | 0.79 | HPGD (0.46) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL28577166 | 0.77 | RECQL (0.44) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL8329830 | 0.77 | CHRM2 (0.37) | RECQLKDM4EPKMGAAMEN1 | |
| SCHEMBL22680078 | 0.76 | GAA (0.43) | HPGDGPR119RECQLEPHX1GAA | |
| SCHEMBL22680079 | 0.76 | GAA (0.43) | HPGDGPR119RECQLEPHX1GAA | |
| SCHEMBL22680073 | 0.76 | GAA (0.43) | HPGDGPR119RECQLEPHX1GAA | |
| SCHEMBL7141622 | 0.74 | HPGD (0.49) | HPGDGPR119RECQLEPHX1KDM4E | |
| SCHEMBL8333352 | 0.74 | TSHR (0.36) | HPGDRECQLGAAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |