Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 12/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20997590 | 0.82 | HTR2A (0.55) | KDM1AKCNH2KDM1BHTR2AHTR2C | |
| SCHEMBL21279715 | 0.82 | SLC6A3 (0.31) | KDM1AHTR2AHTR2CHTR2B | |
| SCHEMBL20202734 | 0.82 | HTR2A (0.55) | KDM1AKCNH2KDM1BHTR2AHTR2C | |
| SCHEMBL808747 | 0.82 | HTR2A (0.55) | KDM1AKCNH2KDM1BHTR2AHTR2C | |
| SCHEMBL13192766 | 0.82 | HTR2A (0.55) | KDM1AKCNH2KDM1BHTR2AHTR2C | |
| SCHEMBL808663 | 0.82 | HTR2A (0.55) | KDM1AKCNH2KDM1BHTR2AHTR2C | |
| SCHEMBL8329695 | 0.81 | KDM1A (0.41) | KDM1AKCNH2KDM1BHTR2AHTR2C | |
| SCHEMBL23995537 | 0.74 | KDM1A (0.70) | KDM1AKCNH2KDM1BHTR2AHTR2C | |
| SCHEMBL13262730 | 0.74 | ESR2 (0.47) | — | |
| SCHEMBL19444133 | 0.74 | KDM1A (0.70) | KDM1AKCNH2KDM1BHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |