Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329013 | 0.81 | ACHE (0.51) | ACHEMEN1KMT2AATMPOLB | |
| SCHEMBL8709040 | 0.80 | CTSS (0.43) | ACHEMEN1KMT2AATM | |
| SCHEMBL8328840 | 0.77 | CARM1 (0.42) | MAPTMAPK1 | |
| SCHEMBL18704971 | 0.75 | MEN1 (0.55) | MEN1KMT2AATMPOLBRAB9A | |
| SCHEMBL8331028 | 0.74 | BCHE (0.49) | ACHE | |
| SCHEMBL8620241 | 0.74 | ACHE (0.41) | ACHEMEN1KMT2AATMPOLB | |
| SCHEMBL8117468 | 0.73 | MAPT (0.67) | MAPTKDM4EMAPK1 | |
| SCHEMBL8328605 | 0.73 | BCHE (0.43) | ACHEMAPK1 | |
| SCHEMBL8326116 | 0.73 | SLC6A4 (0.47) | — | |
| SCHEMBL25803201 | 0.70 | HRH3 (0.55) | MEN1KMT2AATMPOLBRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |