Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.37 |
| ▸ | DRD3 | P35462 | 4/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8331028 | 0.89 | BCHE (0.49) | BCHEACHEBACE1DRD2DRD3 | |
| SCHEMBL7491973 | 0.79 | OPRK1 (0.38) | DRD2DRD3DRD4 | |
| SCHEMBL8326116 | 0.77 | SLC6A4 (0.47) | — | |
| SCHEMBL8328840 | 0.77 | CARM1 (0.42) | MAPK1 | |
| SCHEMBL8326337 | 0.76 | POLB (0.49) | — | |
| SCHEMBL7488941 | 0.75 | DRD4 (0.50) | CYP3A4DRD3DRD4 | |
| SCHEMBL8329776 | 0.73 | ACHE (0.46) | ACHEMAPK1 | |
| SCHEMBL8328601 | 0.71 | BCHE (0.41) | BCHEACHEBACE1FAAHMLNR | |
| SCHEMBL8624159 | 0.70 | BCHE (0.40) | BCHEACHEBACE1FAAHMLNR | |
| SCHEMBL8325593 | 0.70 | SPHK2 (0.41) | CTSSCTSKMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760368-B1 | PYRIMIDINE DERIVATIVES | NISSHIN FLOUR MILLING CO (JP) | 1999-07-28 | — | — | EP | disclosed |
| EP-0760362-A1 | NOVEL DIAMINOMETHYLIDENE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |
| EP-0760368-A1 | NOVEL PYRIMIDINE DERIVATIVE | NISSHIN FLOUR MILLING CO., LTD. (JP) | 1997-03-05 | — | — | EP | disclosed |