Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16732122 | 0.85 | ALDH1A1 (0.41) | THRBATML3MBTL1ALDH1A1KDM4E | |
| SCHEMBL10028034 | 0.84 | ALDH1A1 (0.39) | THRBATML3MBTL1ALDH1A1KDM4E | |
| SCHEMBL15973183 | 0.81 | ALDH1A1 (0.38) | THRBATML3MBTL1ALDH1A1KDM4E | |
| SCHEMBL10486329 | 0.80 | CYP4F2 (0.38) | THRBATML3MBTL1ALDH1A1KDM4E | |
| SCHEMBL15973848 | 0.79 | PKM (0.36) | THRBATML3MBTL1ALDH1A1KDM4E | |
| SCHEMBL9219742 | 0.76 | CYP4F2 (0.40) | THRBALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL28817661 | 0.76 | CHRM2 (0.43) | ATMALDH1A1CHRM2CHRM1CHRM4 | |
| SCHEMBL19071938 | 0.75 | ALDH1A1 (0.41) | THRBATML3MBTL1ALDH1A1CHRM2 | |
| SCHEMBL7783891 | 0.73 | ALDH1A1 (0.42) | THRBATML3MBTL1ALDH1A1POLB | |
| SCHEMBL8843167 | 0.72 | CHRM2 (0.40) | THRBATML3MBTL1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |