Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.50 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 3/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.41 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.41 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330266 | 0.84 | KDM1A (0.46) | KDM1AKDM1BGPR88FFAR1 | |
| SCHEMBL8330750 | 0.84 | KDM1A (0.46) | KDM1AKDM1BDPP4DPP8DPP9 | |
| SCHEMBL8335020 | 0.82 | KDM1A (0.44) | KDM1AKDM1BDPP4DPP9GPR88 | |
| SCHEMBL6753585 | 0.79 | HTR2A (0.42) | KDM1ADPP4DPP8DPP9DPP7 | |
| SCHEMBL6753587 | 0.79 | HTR2A (0.42) | KDM1ADPP4DPP8DPP9DPP7 | |
| SCHEMBL5677229 | 0.71 | GPR88 (0.45) | KDM1AKDM1BDPP4GPR88FFAR1 | |
| SCHEMBL10288349 | 0.71 | KDM1A (0.56) | KDM1AKDM1BDPP4GPR88CES2 | |
| SCHEMBL5675810 | 0.71 | KDM1A (0.56) | KDM1AKDM1BDPP4GPR88CES2 | |
| SCHEMBL10288626 | 0.71 | KDM1A (0.56) | KDM1AKDM1BDPP4GPR88CES2 | |
| SCHEMBL8333820 | 0.71 | FFAR1 (0.42) | DPP4DPP9FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753709-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-19 | — | — | US | disclosed |