Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 13/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6753587 | 1.00 | HTR2A (0.42) | HTR2AHTR2CHTR2BKDM1ADPP4 | |
| SCHEMBL8329899 | 0.79 | KDM1A (0.50) | KDM1ADPP4DPP8DPP9DPP7 | |
| SCHEMBL8333596 | 0.78 | SLC9A1 (0.47) | HTR2AHTR2CHTR2B | |
| SCHEMBL7003744 | 0.77 | DRD2 (0.42) | — | |
| SCHEMBL8331070 | 0.76 | HTR2C (0.44) | HTR2AHTR2CHTR2BKDM1AMAOB | |
| SCHEMBL7002740 | 0.76 | MAOA (0.51) | HTR2CKDM1AMAOB | |
| SCHEMBL8330435 | 0.75 | KDM1A (0.49) | HTR2AHTR2CHTR2BKDM1A | |
| SCHEMBL18272444 | 0.74 | SLC9A1 (0.47) | HTR2AHTR2CHTR2BKDM1AMAOB | |
| SCHEMBL20202735 | 0.74 | SLC9A1 (0.47) | HTR2AHTR2CHTR2BKDM1AMAOB | |
| SCHEMBL6753602 | 0.74 | KDM1A (0.49) | HTR2CKDM1AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6713483-B1 | TREATING PLATELET AGGREGATION DISORDER | ASTRAZENECA AB (SE) | 2004-03-30 | — | — | US | disclosed |
| EP-1232156-B1 | [1,2,3]-TRIAZOLO[4,5-d]PYRIMIDINE DERIVATIVES AS ANTI-THROMBOTIC AGENTS | ASTRAZENECA AB (SE) | 2003-06-04 | — | — | EP | disclosed |