Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.46 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335020 | 0.89 | KDM1A (0.44) | KDM1AKDM1BGPR88RIPK1OPRM1 | |
| SCHEMBL8329899 | 0.84 | KDM1A (0.50) | KDM1AKDM1BGPR88FFAR1 | |
| SCHEMBL8330750 | 0.83 | KDM1A (0.46) | KDM1AKDM1BGPR88RIPK1FFAR1 | |
| SCHEMBL8331376 | 0.77 | MEN1 (0.36) | OPRM1 | |
| SCHEMBL8333857 | 0.76 | F2R (0.37) | OPRM1 | |
| SCHEMBL8333635 | 0.71 | HTR2A (0.44) | — | |
| SCHEMBL8089391 | 0.70 | MTNR1B (0.52) | KDM1AKDM1BFFAR1 | |
| SCHEMBL8089388 | 0.70 | MTNR1B (0.52) | KDM1AKDM1BFFAR1 | |
| SCHEMBL23993612 | 0.69 | KDM1A (0.58) | KDM1AKDM1BFFAR1 | |
| SCHEMBL16591229 | 0.69 | KDM1A (0.58) | KDM1AKDM1BFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753709-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-19 | — | — | US | disclosed |