Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | EDNRA | P25101 | 2/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28195452 | 0.88 | ALDH1A1 (0.52) | ALDH1A1KDM4ENCF1CYP1A2CYP3A4 | |
| SCHEMBL27216809 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KDM4ENCF1CYP1A2CYP3A4 | |
| SCHEMBL28069309 | 0.80 | NCF1 (0.46) | ALDH1A1KDM4ENCF1CYP1A2CYP3A4 | |
| SCHEMBL22189995 | 0.77 | ALDH1A1 (0.42) | ALDH1A1KDM4ENCF1CYP1A2CYP3A4 | |
| SCHEMBL7486790 | 0.76 | NCF1 (0.48) | ALDH1A1KDM4ENCF1CYP1A2CYP3A4 | |
| SCHEMBL28227064 | 0.74 | ALDH1A1 (0.60) | ALDH1A1KDM4ECYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2112739 | 0.74 | CYP2D6 (0.45) | ALDH1A1KDM4ENCF1CYP1A2CYP3A4 | |
| SCHEMBL16151154 | 0.74 | LOXL2 (0.45) | ALDH1A1KDM4ENCF1CYP1A2CYP3A4 | |
| SCHEMBL5402382 | 0.74 | LOXL2 (0.41) | ALDH1A1NCF1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9434224 | 0.73 | PTPN1 (0.43) | ALDH1A1KDM4ECYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556381-B1 | N-(4-PYRIDYL OR 4-QUINOLINYL) ARYLACETAMIDE PESTICIDES | DOW AGROSCIENCES LLC (US) | 1999-04-28 | — | — | EP | claimed |