Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 4/20 | 0.34 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.32 |
| ▸ | POLQ | O75417 | 1/20 | 0.32 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328825 | 0.88 | SSTR4 (0.38) | MAPTSSTR4DGAT2KDM4ETRPM8 | |
| SCHEMBL8327868 | 0.82 | MAPT (0.38) | MAPTLIMK1POLQLIMK2TRPM8 | |
| SCHEMBL8745915 | 0.78 | CYP3A4 (0.39) | KDM4ECYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL8745950 | 0.77 | CYP3A4 (0.39) | KDM4ECYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL9028568 | 0.76 | SCN9A (0.37) | KDM4EALDH1A1KMT2A | |
| SCHEMBL8328842 | 0.75 | NPC1 (0.38) | MAPTSSTR4TRPM8ALDH1A1 | |
| SCHEMBL8802627 | 0.74 | SSTR4 (0.37) | MAPTSSTR4KDM4ETRPM8ALDH1A1 | |
| SCHEMBL8745947 | 0.73 | RIPK1 (0.36) | KDM4ECYP3A4TSHRHSD17B10TDP1 | |
| SCHEMBL8745954 | 0.72 | KDM4E (0.39) | MAPTKDM4ECYP3A4TSHRHSD17B10 | |
| SCHEMBL8745946 | 0.72 | KDM4E (0.39) | KDM4ECYP3A4TSHRHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758321-B1 | 3-SUBSTITUTED PYRIDINE COMPOUNDS AND DERIVATIVES THEREOF AS HERBICIDES | ZENECA LTD (GB) | 1999-04-21 | — | — | EP | disclosed |
| US-5763357-A | HERBICIDES | ZENECA LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| EP-0758321-A1 | 3-SUBSTITUTED PYRIDINE COMPOUNDS AND DERIVATIVES THEREOF AS HERBICIDES | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| US-5595958-A | HERBICIDES | ZENECA LIMITED (GB) | 1997-01-21 | — | — | US | disclosed |
| WO-1995029893-A1 | 3-SUBSTITUTED PYRIDINE COMPOUNDS AND DERIVATIVES THEREOF AS HERBICIDES | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |