Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8745915 | 0.85 | CYP3A4 (0.39) | KDM4EKMT2ACYP3A4TSHRHSD17B10 | |
| SCHEMBL8745950 | 0.84 | CYP3A4 (0.39) | KDM4EKMT2ACYP3A4TSHRHSD17B10 | |
| SCHEMBL8745946 | 0.81 | KDM4E (0.39) | KDM4EKMT2ACYP3A4TSHRHSD17B10 | |
| SCHEMBL8745923 | 0.81 | ACP3 (0.37) | KDM4EKMT2ACYP3A4TSHRHSD17B10 | |
| SCHEMBL9028568 | 0.81 | SCN9A (0.37) | KDM4EKMT2ACNR2MAPK1POLB | |
| SCHEMBL8745904 | 0.81 | RBP4 (0.37) | KDM4EKMT2ACNR2HPGDSMN1; SMN2 | |
| SCHEMBL8328825 | 0.77 | SSTR4 (0.38) | KDM4EKMT2APOLBMAPT | |
| SCHEMBL8745942 | 0.74 | CYP3A4 (0.37) | KDM4EKMT2ACYP3A4TSHRHSD17B10 | |
| SCHEMBL8330141 | 0.72 | MAPT (0.34) | KDM4EKMT2ACYP3A4TSHRHSD17B10 | |
| SCHEMBL9028891 | 0.72 | LIMK1 (0.37) | KDM4EKMT2ACNR2MAPK1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758323-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| WO-1995029898-A1 | HERBICIDAL HYDROXYBENZYL-SUBSTITUTED HETEROARYL COMPOUNDS AND DERIVATIVES THEREOF | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |