Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | SSTR4 | P31391 | 6/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328825 | 0.85 | SSTR4 (0.38) | NPC1POLBTRPM8GAAMAPT | |
| SCHEMBL9028582 | 0.84 | SCN9A (0.40) | NPC1POLB | |
| SCHEMBL8326882 | 0.81 | MAPT (0.40) | NPC1POLBTRPM8GAAMAPT | |
| SCHEMBL8330141 | 0.75 | MAPT (0.34) | TRPM8MAPTSSTR4ALDH1A1 | |
| SCHEMBL8745942 | 0.75 | CYP3A4 (0.37) | POLBALDH1A1 | |
| SCHEMBL9028593 | 0.73 | CNR1 (0.40) | — | |
| SCHEMBL9028568 | 0.72 | SCN9A (0.37) | POLBALDH1A1 | |
| SCHEMBL8802627 | 0.71 | SSTR4 (0.37) | NPC1POLBTRPM8GAAMAPT | |
| SCHEMBL9028891 | 0.71 | LIMK1 (0.37) | POLBALDH1A1 | |
| SCHEMBL8327868 | 0.70 | MAPT (0.38) | TRPM8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758321-B1 | 3-SUBSTITUTED PYRIDINE COMPOUNDS AND DERIVATIVES THEREOF AS HERBICIDES | ZENECA LTD (GB) | 1999-04-21 | — | — | EP | disclosed |
| US-5763357-A | HERBICIDES | ZENECA LIMITED (GB) | 1998-06-09 | — | — | US | disclosed |
| EP-0758321-A1 | 3-SUBSTITUTED PYRIDINE COMPOUNDS AND DERIVATIVES THEREOF AS HERBICIDES | ZENECA LIMITED (GB) | 1997-02-19 | — | — | EP | disclosed |
| US-5595958-A | HERBICIDES | ZENECA LIMITED (GB) | 1997-01-21 | — | — | US | disclosed |
| WO-1995029893-A1 | 3-SUBSTITUTED PYRIDINE COMPOUNDS AND DERIVATIVES THEREOF AS HERBICIDES | ZENECA LIMITED (GB) | 1995-11-09 | — | — | WO | disclosed |