Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8329597 | 0.96 | TDP1 (0.57) | TDP1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL19415629 | 0.89 | MEN1 (0.58) | TDP1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL8331526 | 0.88 | ALDH1A1 (0.48) | TDP1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL20360933 | 0.87 | TDP1 (0.53) | TDP1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL20360840 | 0.85 | TDP1 (0.51) | TDP1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL8329525 | 0.85 | TDP1 (0.47) | TDP1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL7486384 | 0.84 | TDP1 (0.47) | TDP1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL10850237 | 0.84 | L3MBTL1 (0.49) | TDP1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL9518730 | 0.84 | L3MBTL1 (0.49) | TDP1MEN1KMT2AL3MBTL1MAPK1 | |
| SCHEMBL22281399 | 0.82 | TDP1 (0.45) | TDP1MEN1KMT2AL3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |