Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.33 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | APOL1 | O14791 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8335020 | 0.88 | KDM1A (0.44) | MEN1KMT2ADPP4DPP9OPRM1 | |
| SCHEMBL8333857 | 0.86 | F2R (0.37) | MEN1KMT2AKCNE1KCNQ1DPP4 | |
| SCHEMBL8330324 | 0.84 | MTNR1B (0.39) | — | |
| SCHEMBL8716292 | 0.82 | KDM1A (0.35) | DPP4DPP9 | |
| SCHEMBL8331482 | 0.78 | HTR2C (0.43) | OPRM1 | |
| SCHEMBL8330266 | 0.77 | KDM1A (0.46) | OPRM1 | |
| SCHEMBL8331862 | 0.76 | APP (0.38) | SLC6A4 | |
| SCHEMBL8331864 | 0.76 | APP (0.38) | SLC6A4 | |
| SCHEMBL9019896 | 0.74 | MTNR1B (0.49) | — | |
| SCHEMBL8096217 | 0.74 | MTNR1B (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5753709-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-19 | — | — | US | claimed |
| US-5889031-A | CONTROLLING CIRCADIAN RHYTHMS | BRISTOL-MYERS SQUIBB COMPNAY (US) | 1999-03-30 | — | — | US | disclosed |
| US-5753709-A | N-acyl-2 aryl cyclopropylmethylamine derivatives as melatonergics | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-05-19 | — | — | US | disclosed |