SCHEMBL8330396

SCHEMBL8330396

CC(=O)CC(=O)C[Si](C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
KDM6B O15054 1/20 0.44
KDM5C P41229 1/20 0.44
EGLN1 Q9GZT9 1/20 0.44
PHF8 Q9UPP1 1/20 0.44
KDM2A Q9Y2K7 1/20 0.44
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
HTT P42858 2/20 0.35
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
TRPA1 O75762 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6526896 0.76
SCHEMBL3917981 0.75 MGAM (0.42) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL235434 0.75 KDM4E (0.58) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL29550595 0.74 MGAM (0.41) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL3910773 0.72 MGAM (0.44) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL3519320 0.72 KDM4E (0.55) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL10936077 0.72 KDM4E (0.55) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL28706026 0.72 KDM4E (0.55) KDM4EKDM6BKDM5CEGLN1PHF8
SCHEMBL10984500 0.71
SCHEMBL28609824 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0792195-A4 NON-AMINIC PHOTORESIST ADHESION PROMOTERS FOR MICROELECTRONIC APPLICATIONS COMPLEX FLUID SYSTEMS INC (US) 1999-05-26 EP claimed
EP-0792195-A1 NON-AMINIC PHOTORESIST ADHESION PROMOTERS FOR MICROELECTRONIC APPLICATIONS COMPLEX FLUID SYSTEMS, INC. (US) 1997-09-03 EP claimed
WO-1996015861-A1 NON-AMINIC PHOTORESIST ADHESION PROMOTERS FOR MICROELECTRONIC APPLICATIONS COMPLEX FLUID SYSTEMS, INC. (US) 1996-05-30 WO claimed
EP-0792195-A4 NON-AMINIC PHOTORESIST ADHESION PROMOTERS FOR MICROELECTRONIC APPLICATIONS COMPLEX FLUID SYSTEMS INC (US) 1999-05-26 EP disclosed
EP-0792195-A1 NON-AMINIC PHOTORESIST ADHESION PROMOTERS FOR MICROELECTRONIC APPLICATIONS COMPLEX FLUID SYSTEMS, INC. (US) 1997-09-03 EP disclosed
WO-1996015861-A1 NON-AMINIC PHOTORESIST ADHESION PROMOTERS FOR MICROELECTRONIC APPLICATIONS COMPLEX FLUID SYSTEMS, INC. (US) 1996-05-30 WO disclosed