Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | FNTA | P49354 | 3/20 | 0.41 |
| ▸ | FNTB | P49356 | 3/20 | 0.41 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328528 | 0.81 | MEN1 (0.49) | CYP19A1MAPTFNTAFNTBPGGT1B | |
| SCHEMBL8446596 | 0.75 | CYP19A1 (0.41) | CYP19A1MAPTFNTAFNTBPGGT1B | |
| SCHEMBL8323517 | 0.75 | KCNJ1 (0.46) | CYP19A1MAPTFNTAFNTBKCNJ1 | |
| SCHEMBL8324619 | 0.75 | KCNJ1 (0.46) | CYP19A1MAPTFNTAFNTBKCNJ1 | |
| SCHEMBL8328937 | 0.73 | MAPT (0.42) | CYP19A1MAPTTDP1L3MBTL1THRB | |
| SCHEMBL31257790 | 0.71 | MEN1 (0.61) | CYP19A1MAPTCYP1A2CYP3A4TSHR | |
| SCHEMBL16089350 | 0.71 | VCAM1 (0.61) | MAPTTHRBKCNJ1KCNH2PGR | |
| SCHEMBL57257 | 0.71 | VCAM1 (0.61) | MAPTTHRBKCNJ1KCNH2PGR | |
| SCHEMBL27214761 | 0.69 | KCNJ1 (0.55) | MAPTTHRBKCNJ1KCNH2PGR | |
| Selenium SCHEMBL9497333 | 0.69 | VCAM1 (0.59) | MAPTTHRBKCNJ1KCNH2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640595-B1 | SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMA CO LTD (JP) | 1999-03-24 | — | — | EP | disclosed |
| CN-1039228-C | Novel substituted tert-amino compund | YAMANOUCHI PHARMA CO LTD (JP) | 1998-07-22 | — | — | CN | disclosed |
| US-5538976-A | ANTICARCINOGENIC AGENTS AND ENZYME INHIBITORS FOR AROMATASE | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1996-07-23 | — | — | US | disclosed |
| EP-0640595-A1 | NOVEL SUBSTITUTED TERTIARY AMINO COMPOUND OR SALT THEREOF | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-03-01 | — | — | EP | disclosed |
| CN-1079962-A | New substituted tertiary amine compound and salt thereof | YAMANOUCHI PHARMA CO LTD (JP) | 1993-12-29 | — | — | CN | disclosed |