Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 7/20 | 0.33 |
| ▸ | NOS1 | P29475 | 6/20 | 0.33 |
| ▸ | NOS3 | P29474 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328137 | 0.81 | NOS2 (0.51) | NOS2NOS1NOS3 | |
| SCHEMBL7798225 | 0.80 | PDE10A (0.37) | NOS2NOS1 | |
| SCHEMBL5672155 | 0.80 | NOS2 (0.36) | NOS2NOS1NOS3 | |
| SCHEMBL13040665 | 0.80 | NOS2 (0.42) | NOS2NOS1NOS3 | |
| SCHEMBL8329772 | 0.80 | NOS2 (0.39) | NOS2NOS1NOS3 | |
| SCHEMBL2834751 | 0.80 | NOS1 (0.44) | NOS2NOS1NOS3 | |
| SCHEMBL6164054 | 0.79 | NOS2 (0.36) | NOS2NOS1NOS3 | |
| SCHEMBL2830408 | 0.78 | NOS1 (0.57) | NOS2NOS1NOS3 | |
| SCHEMBL8326929 | 0.77 | NOS2 (0.48) | NOS2NOS1NOS3 | |
| SCHEMBL8329387 | 0.77 | NOS2 (0.55) | NOS2NOS1NOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5972975-A | Substituted 2-aminopyridines as inhibitors of nitric oxide synthase | MERCK & CO., INC. (US) | 1999-10-26 | — | — | US | disclosed |
| WO-1996018616-A1 | SUBSTITUTED 2-AMINOPYRIDINES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | disclosed |