Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6929672 | 0.81 | CHRM2 (0.58) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8336470 | 0.79 | KDM4E (0.54) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6768593 | 0.78 | KDM4E (0.53) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL6768941 | 0.75 | SIGMAR1 (0.55) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6768523 | 0.71 | KDM4E (0.50) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL6768498 | 0.71 | SIGMAR1 (0.55) | GAAALDH1A1MAPTHTTSMN1; SMN2 | |
| SCHEMBL18616798 | 0.71 | ALDH1A1 (0.55) | GAAALDH1A1MAPTALOX15TSHR | |
| SCHEMBL8307770 | 0.70 | KDM4E (0.49) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8335230 | 0.69 | NOTUM (0.48) | GAACHRM2CHRM4CHRM1CHRM3 | |
| SCHEMBL8336952 | 0.69 | GAA (0.45) | GAAALDH1A1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999002145-A1 | COMBINATION DRUG THERAPIES COMPRISING AMINOGLYCOSIDE ANTIBIOTICS AND N,N'-DISUBSTITUTED GUANIDINES | CAMBRIDGE NEUROSCIENCE, INC. (US) | 1999-01-21 | — | — | WO | disclosed |