Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CRHBP | P24387 | 1/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7486384 | 0.83 | TDP1 (0.47) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL8331526 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL8330632 | 0.77 | ALDH1A1 (0.41) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL9518730 | 0.75 | L3MBTL1 (0.49) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL10850237 | 0.75 | L3MBTL1 (0.49) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL24506841 | 0.74 | ALDH1A1 (0.38) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL8329597 | 0.72 | TDP1 (0.57) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL30932946 | 0.71 | L3MBTL1 (0.44) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL20782771 | 0.71 | ALDH1A1 (0.36) | ALDH1A1TSHRTDP1MEN1KMT2A | |
| SCHEMBL3328503 | 0.71 | ALDH1A1 (0.44) | ALDH1A1TSHRTDP1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5908863-A | ANTIGROWTH AGENT FOR BONES | DOMPE' S.P.A. (IT) | 1999-06-01 | — | — | US | disclosed |
| EP-0792878-A2 | Geminal carboxylic acids and esters thereof, pharmaceutical formulations containing them useful in the treatment of bone dysmetabolism | Dompé S.P.A. (IT) | 1997-09-03 | — | — | EP | disclosed |