Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACAT1 | P24752 | 1/20 | 0.74 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323178 | 0.98 | ACAT1 (0.75) | ACAT1SOAT1POLBTRPV1PDE4A | |
| SCHEMBL8322582 | 0.93 | ACAT1 (0.72) | ACAT1SOAT1 | |
| SCHEMBL6636784 | 0.93 | ACAT1 (0.72) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8327206 | 0.92 | ACAT1 (0.81) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8328078 | 0.92 | ACAT1 (0.66) | ACAT1SOAT1 | |
| SCHEMBL8324521 | 0.91 | ACAT1 (0.80) | ACAT1SOAT1 | |
| SCHEMBL6639853 | 0.91 | ACAT1 (0.85) | ACAT1SOAT1PDE4AKCNH2 | |
| SCHEMBL8327532 | 0.91 | ACAT1 (0.73) | ACAT1SOAT1 | |
| SCHEMBL8330841 | 0.91 | ACAT1 (0.69) | ACAT1SOAT1TRPV1PDE4AKCNH2 | |
| SCHEMBL6635258 | 0.91 | ACAT1 (0.89) | ACAT1SOAT1PDE4AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0947515-A1 | NOVEL NAPHTHYRIDINE DERIVATIVES | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1999-10-06 | — | — | EP | disclosed |