Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468002 | 0.67 | DHODH (0.37) | DHODHNR1H2 | |
| SCHEMBL5639524 | 0.60 | DHODH (0.58) | BRD4DHODHNR1H2 | |
| SCHEMBL6993576 | 0.60 | CYP4A11 (0.35) | PPARANR1H2 | |
| SCHEMBL10838297 | 0.60 | HTR1A (0.53) | — | |
| SCHEMBL5639439 | 0.59 | MPO (0.53) | BRD4DHODHNR1H2 | |
| SCHEMBL13792687 | 0.59 | PPARA (0.65) | PPARANR1H2 | |
| SCHEMBL5746834 | 0.58 | NR1H2 (0.50) | NR1H2 | |
| SCHEMBL1560634 | 0.58 | CYP4A11 (0.69) | PPARANR1H2 | |
| SCHEMBL17081008 | 0.57 | BRD4 (0.57) | BRD4 | |
| SCHEMBL15492617 | 0.57 | TDP1 (0.54) | PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |