Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | KLK7 | P49862 | 7/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | KLK5 | Q9Y337 | 6/20 | 0.35 |
| ▸ | PRKCG | P05129 | 4/20 | 0.35 |
| ▸ | PRKCB | P05771 | 4/20 | 0.35 |
| ▸ | PRKCH | P24723 | 4/20 | 0.35 |
| ▸ | PRKCE | Q02156 | 4/20 | 0.35 |
| ▸ | PRKCQ | Q04759 | 4/20 | 0.35 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.35 |
| ▸ | PRKCA | P17252 | 3/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.33 |
| ▸ | PRKCI | P41743 | 2/20 | 0.33 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.33 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8323234 | 0.93 | KLK7 (0.36) | DHODHKLK7NR1H2KLK5PRKCG | |
| SCHEMBL8467659 | 0.84 | GABRG2 (0.39) | KLK7KLK5PRSS1PRSS2PRSS3 | |
| SCHEMBL7366878 | 0.83 | ITGB3 (0.38) | KLK7ITGB3ITGA2BITGAV | |
| SCHEMBL8330616 | 0.82 | ITGB3 (0.46) | ITGB3ITGA2BITGAV | |
| SCHEMBL8467321 | 0.80 | GABRA1 (0.35) | DHODHKLK7PRKCGPRKCBPRKCE | |
| SCHEMBL8328325 | 0.71 | ITGB3 (0.40) | ITGB3ITGA2BMEN1KMT2AITGAV | |
| SCHEMBL5639524 | 0.69 | DHODH (0.58) | DHODHNR1H2 | |
| SCHEMBL7544674 | 0.68 | ITGB3 (0.39) | ITGB3ITGA2BITGAV | |
| SCHEMBL5639439 | 0.68 | MPO (0.53) | DHODHNR1H2MEN1KMT2A | |
| SCHEMBL8330762 | 0.67 | BRD4 (0.37) | DHODHNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869787-A4 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORP (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0869787-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| WO-1997024119-A1 | VITRONECTIN RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-07-10 | — | — | WO | disclosed |