Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8328141 | 0.89 | HRH3 (0.37) | HRH3GNAO1 | |
| SCHEMBL3636427 | 0.79 | CYP1A2 (0.38) | — | |
| SCHEMBL7957882 | 0.74 | CYP1A2 (0.44) | HRH3GNAO1 | |
| SCHEMBL332080 | 0.73 | GNAO1 (0.45) | HRH3GNAO1 | |
| Hydrochloric Acid SCHEMBL11196770 | 0.72 | GNAO1 (0.43) | HRH3GNAO1 | |
| SCHEMBL161117 | 0.72 | HRH3 (0.37) | HRH3 | |
| Hydrochloric Acid SCHEMBL3670602 | 0.71 | GNAO1 (0.48) | HRH3GNAO1 | |
| SCHEMBL9384345 | 0.71 | GNAO1 (0.44) | HRH3GNAO1 | |
| Hydrochloric Acid SCHEMBL4486629 | 0.71 | GNAO1 (0.48) | HRH3GNAO1 | |
| SCHEMBL8563966 | 0.70 | HRH3 (0.40) | HRH3GNAO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925642-A | ANTITUMOR, ANTIMETASTASIS AGENTS; DRUG RESISTANCE MODULATORS; SYNERGISTIC MIXTURES WITH ANTIBIOTICS AND CYTOSTATIC AGENTS; SIDE EFFECT REDUCTION | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-07-20 | — | — | US | disclosed |