Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.31 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.31 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.30 |
| ▸ | NOS2 | P35228 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330912 | 0.89 | HRH3 (0.34) | HRH3GNAO1 | |
| SCHEMBL2767420 | 0.76 | CYP1A2 (0.52) | HRH3ITGB3ITGA2BCYP1A2TPSAB1 | |
| SCHEMBL237382 | 0.76 | ITGB3 (0.47) | HRH3ITGB3ITGA2BFAAHCYP1A2 | |
| Hydrochloric Acid SCHEMBL10840761 | 0.73 | ITGB3 (0.46) | HRH3ITGB3ITGA2BFAAHCYP1A2 | |
| SCHEMBL8097693 | 0.73 | ITGB3 (0.46) | HRH3ITGB3ITGA2BFAAHCYP1A2 | |
| SCHEMBL2014329 | 0.72 | HRH3 (0.43) | HRH3ITGB3ITGA2BFAAHTPSAB1 | |
| SCHEMBL946347 | 0.71 | SIGMAR1 (0.39) | NOS1NOS2 | |
| SCHEMBL295542 | 0.71 | NOS1 (0.50) | CYP1A2NOS1NOS2 | |
| SCHEMBL3975826 | 0.71 | NOS1 (0.31) | NOS1NOS2 | |
| SCHEMBL331124 | 0.71 | HRH3 (0.47) | HRH3ITGB3ITGA2BFAAHCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925642-A | ANTITUMOR, ANTIMETASTASIS AGENTS; DRUG RESISTANCE MODULATORS; SYNERGISTIC MIXTURES WITH ANTIBIOTICS AND CYTOSTATIC AGENTS; SIDE EFFECT REDUCTION | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1999-07-20 | — | — | US | disclosed |