Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 2/20 | 0.38 |
| ▸ | BID | P55957 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.38 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.38 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.38 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.38 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.36 |
| ▸ | CTSG | P08311 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20164914 | 0.99 | ALOX5 (0.47) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL573935 | 0.84 | ALOX5 (0.60) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL574604 | 0.83 | ALOX5 (0.58) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL574394 | 0.83 | ALOX5 (0.58) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL574233 | 0.83 | ALOX5 (0.53) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL574535 | 0.83 | CA2 (0.43) | TP53TSHRTDP1HSP90AA1 | |
| SCHEMBL2914269 | 0.77 | ALOX5 (0.49) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL2914268 | 0.76 | ALOX5 (0.46) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL27456560 | 0.76 | ALOX5 (0.46) | ALOX5PTGS2TYRBIDMCL1 | |
| SCHEMBL8319104 | 0.75 | ALOX5 (0.57) | ALOX5PTGS2TYRBIDMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805672-A4 | METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH | HOMOLA ANDREW M (US) | 1999-06-30 | — | — | EP | disclosed |
| EP-0805672-A1 | METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH | HOMOLA, Andrew M. (US) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022078-A1 | METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH | HOMOLA ANDREW M (US) | 1996-07-25 | — | — | WO | disclosed |