SCHEMBL574233

SCHEMBL574233

CCCCc1cccc(Cl)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.53
PTGS2 P35354 1/20 0.53
EGFR P00533 2/20 0.48
ERBB2 P04626 1/20 0.48
HSP90AA1 P07900 1/20 0.47
IAPP P10997 1/20 0.46
CFTR P13569 4/20 0.46
ELANE P08246 1/20 0.44
CTSG P08311 1/20 0.44
GABRA1 P14867 1/20 0.43
GABRB2 P47870 1/20 0.43
TYR P14679 2/20 0.43
BID P55957 3/20 0.42
MCL1 Q07820 3/20 0.42
BCL2L1 Q07817 2/20 0.42
BAK1 Q16611 2/20 0.42
KAT8 Q9H7Z6 2/20 0.42
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
EP300 Q09472 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL573935 0.94 ALOX5 (0.60) ALOX5PTGS2EGFRERBB2HSP90AA1
SCHEMBL574604 0.93 ALOX5 (0.58) ALOX5PTGS2EGFRERBB2HSP90AA1
SCHEMBL574394 0.93 ALOX5 (0.58) ALOX5PTGS2EGFRERBB2HSP90AA1
SCHEMBL1552241 0.88 HSP90AA1 (0.50) ALOX5PTGS2EGFRERBB2HSP90AA1
SCHEMBL11077986 0.88 HSP90AA1 (0.53) ALOX5PTGS2EGFRERBB2HSP90AA1
SCHEMBL201764 0.86 ALOX5 (0.61) ALOX5PTGS2IAPPELANECTSG
Parachlorophenol SCHEMBL8332607 0.84 PTGS2 (0.50) ALOX5PTGS2EGFRERBB2HSP90AA1
Hydrogen Sulfide SCHEMBL28293295 0.84 ALOX5 (0.59) ALOX5PTGS2IAPPELANECTSG
SCHEMBL8624471 0.83 GABRA1 (0.57) ALOX5PTGS2EGFRERBB2HSP90AA1
SCHEMBL8330970 0.83 ALOX5 (0.46) ALOX5PTGS2EGFRERBB2HSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140135297-A1 AQUEOUS VOLATILE ORGANIC COMPOUND FREE DISINFECTANT AND/OR CLEANING COMPOSITION AND METHOD OF PREPARATION ISP INVESTMENTS INC. (US) 2014-05-15 US claimed
WO-2012170841-A1 AN AQUEOUS VOLATILE ORGANIC COMPOUND FREE DISINFECTANT AND/OR CLEANING COMPOSITION AND METHOD OF PREPARATION ISP INVESTMENTS INC. (US) 2012-12-13 WO claimed
EP-2313026-A1 ACTIVE DELIVERY SYSTEM FORMULATIONS Castle Beach, L.L.C. (US) 2011-04-27 EP claimed
US-20100040565-A1 ACTIVE DELIVERY SYSTEMS FORMULATIONS Castle Beach, LLC (US) 2010-02-18 US claimed
WO-2010019680-A1 ACTIVE DELIVERY SYSTEM FORMULATIONS HOMOLA ANDREW M (US) 2010-02-18 WO claimed
EP-1549731-B1 CLEANING AND DISINFECTING COMPOSITION RECKITT BENCKISER INC (US) 2008-12-17 EP claimed
EP-0805672-B1 METHODS, COMPOSITIONS, AND DENTAL DELIVERY SYSTEMS FOR THE PROTECTION OF THE SURFACES OF TEETH HOMOLA ANDREW M (US) 2004-08-25 EP claimed
US-5665333-A Methods, compositions, and dental delivery systems for the protection of the surfaces of teeth PROVSEAL LLC 1997-09-09 US claimed
EP-3528776-B1 REDUCED-ETHANOL MOUTH RINSE FORMULATIONS KENVUE BRANDS LLC (US) 2025-11-26 EP disclosed
EP-4551195-A1 CANNABINOID LIPID PREMIXTURE Fertin Pharma A/S (DK) 2025-05-14 EP disclosed
WO-2025067622-A1 CANNABIDIOL FOR USE IN ALLEVIATING XEROSTOMIA FERTIN PHARMA A/S (DK) 2025-04-03 WO disclosed
CN-119562805-A Cannabinoid lipid premix 费尔廷制药公司 2025-03-04 CN disclosed
EP-3653303-B1 PIPETTE TIP RACK BIOTIX INC (US) 2025-02-26 EP disclosed
US-12201987-B2 Pipette tip rack BIOTIX, INC. (US) 2025-01-21 US disclosed
US-5288480-A Antiplaque antibacterial oral composition COLGATE-PALMOLIVE CO. (US) 1994-02-22 US disclosed
US-5192530-A Solubilizer, enhancing agent to aid retention, and delivery enhancement COLGATE-PALMOLIVE COMPANY (US) 1993-03-09 US disclosed
US-5178851-A Dentifrices treatment with triclosan and carriers COLGATE-PALMOLIVE COMPANY (US) 1993-01-12 US disclosed
US-5080887-A Polyphosphate, bactericide COLGATE-PALMOLIVE COMPANY (US) 1992-01-14 US disclosed
US-4894220-A WATER AND ALCOHOL SOLVENTS, GLYCOL DERIVATIVES AND ESTERS SOLUTIONS COLGATE-PALMOLIVE COMPANY (US) 1990-01-16 US disclosed
WO-1983000333-A1 ANTI-HYPERTENSOR, HETEROCYCLICALLY DI-ORTHOSUBSTITUTED PHENOLS TEULON, JEAN-MARIE 1983-02-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100040565-A1 ACTIVE DELIVERY SYSTEMS FORMULATIONS LIPA, MMP7, CTSA ALOX5 716/4885PTGS2 342/4885EGFR 1614/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.