Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.52 |
| ▸ | RARB | P10826 | 4/20 | 0.52 |
| ▸ | RARG | P13631 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 3/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8332455 | 0.94 | RARA (0.44) | RARARARBRARGOPRD1KCNH2 | |
| SCHEMBL8331104 | 0.90 | RARA (0.41) | RARARARBRARGRAB9AOPRD1 | |
| SCHEMBL8335176 | 0.89 | RARB (0.41) | RARARARBRARGOPRD1PPARG | |
| SCHEMBL8329425 | 0.89 | RARA (0.41) | RARARARBRARGOPRD1KCNH2 | |
| SCHEMBL6592120 | 0.75 | RARA (0.52) | RARARARBRARGPPARG | |
| SCHEMBL24727649 | 0.74 | RARB (0.52) | RARARARBRARGOPRD1KCNH2 | |
| SCHEMBL8772796 | 0.74 | RARB (0.48) | RARARARBRARG | |
| SCHEMBL24727741 | 0.73 | RARB (0.56) | RARARARBRARGGAAOPRD1 | |
| SCHEMBL24727735 | 0.73 | RARA (0.53) | RARARARBRARGOPRD1KCNH2 | |
| SCHEMBL24727712 | 0.72 | RARA (0.57) | RARARARBRARGOPRD1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |