Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 4/20 | 0.52 |
| ▸ | RARB | P10826 | 4/20 | 0.52 |
| ▸ | RARG | P13631 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8333153 | 0.85 | RARA (0.48) | RARARARBRARG | |
| SCHEMBL8331032 | 0.85 | RARA (0.53) | RARARARBRARGALDH1A1MEN1 | |
| SCHEMBL8329653 | 0.84 | RARA (0.37) | RARARARBRARGALDH1A1NPC1 | |
| SCHEMBL8331248 | 0.82 | RARB (0.38) | RARARARBRARG | |
| SCHEMBL8469320 | 0.75 | RARA (0.42) | RARARARBRARGRXFP1 | |
| SCHEMBL8331925 | 0.75 | RARA (0.48) | RARARARBRARGALDH1A1MEN1 | |
| SCHEMBL8330182 | 0.74 | RARA (0.47) | RARARARBRARG | |
| SCHEMBL8329823 | 0.73 | RARA (0.46) | RARARARBRARG | |
| SCHEMBL8329461 | 0.72 | RARA (0.49) | RARARARBRARGNPC1KMT2A | |
| SCHEMBL8327517 | 0.72 | RARA (0.40) | RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |