Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8330895 | 0.71 | RARA (0.39) | RARARARBRARG | |
| SCHEMBL1140826 | 0.70 | RARB (0.60) | RARARARBRARG | |
| SCHEMBL726359 | 0.66 | RARA (0.60) | RARARARBRARG | |
| SCHEMBL27707567 | 0.65 | TAAR1 (0.35) | — | |
| SCHEMBL27707579 | 0.65 | MAOB (0.35) | — | |
| SCHEMBL3533753 | 0.63 | EGFR (0.38) | — | |
| SCHEMBL27618385 | 0.62 | CYP2A6 (0.44) | — | |
| SCHEMBL533382 | 0.62 | CYP2A6 (0.44) | — | |
| SCHEMBL8074245 | 0.62 | TAAR1 (0.35) | RARB | |
| SCHEMBL8089559 | 0.60 | TUBB1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |