Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 4/20 | 0.35 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.33 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081800 | 0.87 | GABRA1 (0.42) | TUBB1NAAASLC13A5ALOX5GABRA1 | |
| SCHEMBL28752781 | 0.85 | HRH3 (0.41) | NAAASLC13A5HTR7 | |
| SCHEMBL8088891 | 0.85 | ALDH1A1 (0.35) | PTGDR2SLC5A2CYP2A6GABRA1GABRB2 | |
| SCHEMBL27588574 | 0.83 | HRH3 (0.47) | HTR7 | |
| SCHEMBL9268604 | 0.81 | ABL1 (0.42) | PTGS2CYP2A6 | |
| SCHEMBL8089506 | 0.81 | ALDH1A1 (0.36) | NPC1RAB9A | |
| SCHEMBL27588559 | 0.79 | KMT2A (0.36) | TUBB1HTR7 | |
| SCHEMBL27606299 | 0.79 | MGAM (0.47) | — | |
| SCHEMBL27588691 | 0.79 | CHEK1 (0.41) | TUBB1NPC1RAB9A | |
| SCHEMBL9416117 | 0.79 | SQOR (0.40) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051394-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037607-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 1999-07-29 | — | — | WO | disclosed |