⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10505470 | 0.77 | — | — | |
| SCHEMBL2689498 | 0.65 | — | — | |
| SCHEMBL15659901 | 0.61 | ALDH1A1 (0.30) | — | |
| SCHEMBL820210 | 0.61 | CTSD (0.32) | — | |
| SCHEMBL13969134 | 0.60 | — | — | |
| SCHEMBL16582527 | 0.54 | CTSD (0.39) | — | |
| SCHEMBL2692984 | 0.54 | KDM4E (0.31) | — | |
| SCHEMBL17866247 | 0.54 | — | — | |
| SCHEMBL4428965 | 0.50 | — | — | |
| SCHEMBL7637933 | 0.50 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337652-B1 | SUPERIOR CATALYSTS FOR PREPARATION OF 3-AMINO-2,2,4,4-TETRAMETHYLTHIETANE VIA THE LEUCKART REACTION | PFIZER INC. (US) | 1992-10-07 | — | — | EP | claimed |
| EP-0337652-A1 | Superior catalysts for preparation of 3-amino-2,2,4,4-tetramethylthietane via the Leuckart reaction | PFIZER INC. (US) | 1989-10-18 | — | — | EP | claimed |
| US-4851548-A | Superior catalysts for preparation of 3-amino-2,2,4,4-tetramethylthietane via the Leuckart reaction | PFIZER INC. (US) | 1989-07-25 | — | — | US | claimed |
| EP-0811012-B1 | METHOD OF PRODUCING L-ASPARTYL-D-ALANINE-N-(THIETHANE-3-YL)-AMIDES | DEGUSSA (DE) | 1999-05-26 | — | — | EP | disclosed |
| US-5874121-A | Method of producing L-aspartyl-D-alanine-N-(thiethane-3-yl)-amides | DEGUSSA AG (DE) | 1999-02-23 | — | — | US | disclosed |
| EP-0811012-A1 | METHOD OF PRODUCING L-ASPARTYL-D-ALANINE-N-(THIETHANE-3-YL)-AMIDES | Degussa Aktiengesellschaft (DE) | 1997-12-10 | — | — | EP | disclosed |
| WO-1996026213-A1 | METHOD OF PRODUCING L-ASPARTYL-D-ALANINE-N-(THIETHANE-3-YL)-AMIDES | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1996-08-29 | — | — | WO | disclosed |
| WO-1996026202-A1 | PROCESS FOR PRODUCING THIETANONES | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1996-08-29 | — | — | WO | disclosed |
| EP-0337652-B1 | SUPERIOR CATALYSTS FOR PREPARATION OF 3-AMINO-2,2,4,4-TETRAMETHYLTHIETANE VIA THE LEUCKART REACTION | PFIZER INC. (US) | 1992-10-07 | — | — | EP | disclosed |
| US-4894464-A | ARTIFICIAL SWEETENERS | PFIZER INC. (US) | 1990-01-16 | — | — | US | disclosed |
| EP-0337652-A1 | Superior catalysts for preparation of 3-amino-2,2,4,4-tetramethylthietane via the Leuckart reaction | PFIZER INC. (US) | 1989-10-18 | — | — | EP | disclosed |
| US-4517379-A | ARTIFICIAL SWEETENER | PFIZER INC. (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0128654-A2 | Gem-diaminoalkane derived sweeteners | CUMBERLAND PACKING CORPORATION (US) | 1984-12-19 | — | — | EP | disclosed |
| EP-0069811-B1 | BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF | PFIZER INC. (US) | 1984-10-24 | — | — | EP | disclosed |
| EP-0034876-B1 | BRANCHED AMIDES OF L-ASPARTYL-D-AMINO ACID DIPEPTIDES AND COMPOSITIONS THEREOF | PFIZER INC. (US) | 1984-08-29 | — | — | EP | disclosed |
| US-4454328-A | SWEETENERS | PFIZER INC. (US) | 1984-06-12 | — | — | US | disclosed |
| US-4411925-A | STABLE SWEETENERS | PFIZER INC. (US) | 1983-10-25 | — | — | US | disclosed |
| US-4399163-A | ARTIFICIAL SWEETENERS | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| EP-0069811-A1 | Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof | PFIZER INC. (US) | 1983-01-19 | — | — | EP | disclosed |
| EP-0034876-A2 | Branched amides of L-aspartyl-D-amino acid dipeptides and compositions thereof | PFIZER INC. (US) | 1981-09-02 | — | — | EP | disclosed |