SCHEMBL820210

SCHEMBL820210

CC1(C)C(=O)C(C)(C)C1=O

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSD P07339 1/20 0.32
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3626473 1.00 CTSD (0.32) CTSDALDH1A1
SCHEMBL15658134 0.82
SCHEMBL16582527 0.79 CTSD (0.39) CTSD
SCHEMBL3166077 0.76
SCHEMBL15659426 0.76
SCHEMBL2689498 0.74
SCHEMBL10589435 0.73 TSHR (0.33)
SCHEMBL13491264 0.71 POLB (0.31)
SCHEMBL3676231 0.71 LMNA (0.43)
SCHEMBL3682464 0.71 LMNA (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12630491-B2 Production of 2,2,4,4-tetramethylcyclobutane-1,3-diol from secondary alcohols and 2,2,4,4-tetramethylcyclobutanedione using homogeneous catalysts EASTMAN CHEMICAL COMPANY (US) 2026-05-19 US claimed
US-12577184-B2 Production of 2,2,4,4-tetramethylcyclobutane-1,3-diol from isobutanol using a homogeneous catalyst EASTMAN CHEMICAL COMPANY (US) 2026-03-17 US claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
CN-120136688-A Preparation method of 2, 4-tetramethyl-1, 3-cyclobutanedione 青岛科技大学 2025-06-13 CN claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
EP-4543841-A2 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES The University of North Carolina at Chapel Hill (US) 2025-04-30 EP claimed
US-20250075147-A1 FRAGRANCE AND FLAVOR COMPOSITIONS COMPRISING NEW FLAVOR AND FRAGRANCE INGREDIENTS OSMO LABS, PBC 2025-03-06 US claimed
EP-4255873-B1 PRODUCTION OF 2,2,4,4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM ISOBUTANOL USING A HOMOGENEOUS CATALYST EASTMAN CHEM CO (US) 2024-12-18 EP claimed
EP-4255881-B1 PRODUCTION OF 2,2,4, 4-TETRAMETHYLCYCLOBUTANE-1, 3-DIOL FROM SECONDARY ALCOHOLS AND 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIONE USING HOMOGENEOUS CATALYSTS EASTMAN CHEM CO (US) 2024-12-18 EP claimed
WO-2023250180-A2 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-12-28 WO claimed
US-20080132742-A1 by hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione; cesium and cobalt promoters; specific cis/trans isomer ratio in order to control glass transition temperatures and/or crystallization rates in copolyesters EASTMAN CHEMICAL COMPANY (US) 2008-06-05 US claimed
US-6797745-B1 Hot melt inks containing styrene or terpene polymers XEROX CORPORATION 2004-09-28 US claimed
US-6117223-A Hot melt inks containing polyketones XEROX CORPORATION (US) 2000-09-12 US claimed
EP-0681564-A1 PROCESS FOR THE MANUFACTURE OF 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIOL EASTMAN CHEMICAL COMPANY (US) 1995-11-15 EP claimed
EP-0600019-B1 PROCESS FOR THE MANUFACTURE OF 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIOL EASTMAN CHEM CO (US) 1995-10-18 EP claimed
WO-1994018146-A1 PROCESS FOR THE MANUFACTURE OF 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIOL EASTMAN CHEMICAL COMPANY (US) 1994-08-18 WO claimed
EP-0600019-A1 PROCESS FOR THE MANUFACTURE OF 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIOL. EASTMAN KODAK CO (US) 1994-06-08 EP claimed
US-5258556-A DISSOLVING DIMETHYLKETENE FROM PYROLYZING ISOBUTYRIC ANHYDRIDE IN 2,2,4,4-TETRAMETHYLCYCLOBUTANE-1,3-DIONE, DIMERIZING DIMETHYLKETENE AND HYDROGENATING RESULTING 2,2,4,4-TETRA-METHYLCYCLOBUTANE-1,3-DIONE EASTMAN KODAK COMPANY (US) 1993-11-02 US claimed
WO-1993004026-A1 PROCESS FOR THE MANUFACTURE OF 2,2,4,4-TETRAMETHYLCYCLOBUTANEDIOL EASTMAN KODAK COMPANY (US) 1993-03-04 WO claimed
US-5169994-A Process for the manufacture of 2,2,4,4-tetramethycyclobutanediol EASTMAN KODAK COMPANY (US) 1992-12-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080132742-A1 by hydrogenation of a 2,2,4,4-tetraalkylcyclobutane-1,3-dione; cesium and cobalt promoters; specific cis/trans isomer ratio in order to control glass transition temperatures and/or crystallization rates in copolyesters CA3, TELO2, CA1 CTSD 1623/4885ALDH1A1 928/4885
US-12630491-B2 Production of 2,2,4,4-tetramethylcyclobutane-1,3-diol from secondary alcohols and 2,2,4,4-tetramethylcyclobutanedione using homogeneous catalysts ADH1C, ADH1A, ADH5 CTSD 4869/4885ALDH1A1 195/4885
US-12577184-B2 Production of 2,2,4,4-tetramethylcyclobutane-1,3-diol from isobutanol using a homogeneous catalyst HAO2, TDO2, THRB CTSD 3941/4885ALDH1A1 723/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.