Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.47 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | RXRB | P28702 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5079256 | 0.84 | TDP1 (0.59) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL446400 | 0.78 | TDP1 (0.69) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL9699955 | 0.77 | TDP1 (0.51) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL28228520 | 0.77 | TDP1 (0.51) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL29212909 | 0.77 | MAPT (0.55) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL27332603 | 0.74 | ACHE (0.56) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL19875749 | 0.74 | TDP1 (0.63) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL19875751 | 0.74 | TDP1 (0.63) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL29212907 | 0.74 | SMN1; SMN2 (0.53) | TDP1MAPTL3MBTL1TNFKLF5 | |
| SCHEMBL28343567 | 0.74 | MAPT (0.58) | TDP1MAPTL3MBTL1TNFKLF5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5962731-A | MODIFY LIPID METABOLISM; SKIN DISORDERS,; AUTOIMMUNE DISEASES; FATTY ACID METABOLISM; ANTITUMOR AGENTS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-10-05 | — | — | US | claimed |
| US-5962731-A | MODIFY LIPID METABOLISM; SKIN DISORDERS,; AUTOIMMUNE DISEASES; FATTY ACID METABOLISM; ANTITUMOR AGENTS | LIGAND PHARMACEUTICALS INCORPORATED (US) | 1999-10-05 | — | — | US | disclosed |